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平臺(tái)編號(hào)：bio-74919
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國(guó)際編號(hào)：ATCC 6227b
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拉丁屬名： Rhizopus stolonifer
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規(guī)格：freeze-dried
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用途：ATCC原裝進(jìn)口
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服務(wù)費(fèi)用：
加載中…… - 訂購(gòu)
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注意事項(xiàng)：僅用于科學(xué)研究或者工業(yè)應(yīng)用等非醫(yī)療目的不可用于人類(lèi)或動(dòng)物的臨床診斷或治療，非藥用，非食用（產(chǎn)品信息以出庫(kù)為準(zhǔn)）
米根霉
Rhizopus stolonifer 菌株拉丁名 (Ehrenberg : Fries) Lind
(ATCC 6227b 菌株編號(hào)
Permits and Restrictions View Permits
Deposited As Rhizopus nigricans Ehrenberg, teleomorph
Strain Designations 菌株別名 C-25B [CBS 382.52, IFO 5781, IFO 6154, IFO 6300, IMI 57762, VKM F-401]
Application produces 11-alpha-hydroxylase produces 17 beta-hydroxysteroid dehydrogenase
Estradiol 17-beta-dehydrogenase-1, Hydroxysteroid dehydrogenase 17 beta, type 1, hydroxysteroid 17-beta dehydrogenase 1 produces chiral alcohols produces steroids transformation of sesquiterpene lactone costunolide reduces 3-methoxy-8(14)-seco-1,3,5(10),9(11)-estratetraene-14,17-dione
Biosafety Level 生物安全等級(jí) 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Product Format提供形式 freeze-dried
Type Strain模式菌株 no
Preceptrol? no
Mating Type mating type plus
Comments 注釋 Hydroxylation of 17 alpha-ethynyl steroids Detoxification of steroids by cytochrome P45011alpha
Medium 培養(yǎng)基 ATCC Medium 336: Potato dextrose agar (PDA)
Growth Conditions 生長(zhǎng)條件
Temperature 培養(yǎng)溫度: 24.0℃
Name of Depositor AF Blakeslee Disclosure This material is cited in a US or other Patent and may not be used to infringe the claims.
Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished.
Cross References參考文獻(xiàn) Nucleotide (GenBank) : Y10414 R.nigricans mRNA for stress protein.
Nucleotide (GenBank) : S50228 steroid hydroxylase cytochrome P-450 [Rhizopus nigricans, ATCC References Abul-Hajj YJ. Stereochemistry of C-1, 2 dehydrogenation of 5 beta-pregnane-3, 11, 20-trione by Septomyxa affinis. J. Biol. Chem. 247: 686-691, 1972. PubMed: 5058221
Zakelj-Mavric M, et al. The bioconversion of 17 alpha-ethynyl steroids with 11 alpha-hydroxylase of Rhizopus nigricans. FEMS Microbiol. Lett. 33: 117-120, 1986.
Mills JS. 10-Fluoro-19-nor steroids. US Patent 3,053,858 dated Sep 11 1962
Gibian H, et al. Production of optically active antipodes. US Patent 3,562,112 dated Feb 9 1971
Lanisnik T, et al. Fungal 17 beta-hydroxysteroid dehydrogenase. FEMS Microbiol. Lett. 78: 49-52, 1992. PubMed: 1334892
Breskvar K, et al. The role of cytochrome P450(11 alpha) in detoxification of steroids in the filamentous fungus Rhizopus nigricans. J. Steroid Biochem. Mol. Biol. 52: 271-275, 1995. PubMed: 7696148
Hudnik-Plevnik T, Cresnar B. Factors affecting the induction of 11 alpha-hydroxylase of progesterone in the filamentous fungus Rhizopus nigricans. J. Steroid Biochem. 35: 749-751, 1990. PubMed: 2362437
Clark AM, Hufford CD. Microbial transformations of the sesquiterpene lactone costunolide. J. Chem. Soc. Perkin Trans. 1979: 3022-3028, 1979.
Kasai M, et al. Enantioselective ester hydrolyses using Rhizopus nigricans: stereoselective synthesis and absolute stereochemistry of (-)-cis-and (-)-trans-1-hydroxy-4-methyl-1,2,3,4-tetrahydronaphthalene. Can. J. Chem. 63: 1287-1291, 1985.
Zakelj-Mavric M, Belic I. Hydroxylation of steroids with 11alpha-hydroxylase of Rhizopus nigricans. J. Steroid Biochem. 28: 197-201, 1987. PubMed: 3498094
