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首頁>美國ATCC>ATCC菌種類>CBS 7987 [ATCC MYA-178, CD 36, NCPF 3949, NRRL Y-17841]
CBS 7987 [ATCC MYA-178, CD 36, NCPF 3949, NRRL Y-17841]
    CBS 7987 [ATCC MYA-178, CD 36, NCPF 3949, NRRL Y-17841]
  • 平臺編號:bio-104449
  • 國際編號:ATCC MYA-646
  • 拉丁屬名: Candida dubliniensis
  • 規(guī)格: frozen
  • 用途:ATCC原裝進口
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  • 注意事項:僅用于科學研究或者工業(yè)應(yīng)用等非醫(yī)療目的不可用于人類或動物的臨床診斷或治療,非藥用,非食用(產(chǎn)品信息以出庫為準)

Candida dubliniensis Sullivan et al. 拉丁名
(ATCC? MYA-646?) 統(tǒng)一編號
Deposited As Candida dubliniensis Sullivan et al., anamorph
Strain Designations 別名 CBS 7987 [ATCC MYA-178, CD 36, NCPF 3949, NRRL Y-17841]
Biosafety Level 生物安全等級 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Product Format 提供形式 frozen
Storage Conditions 
Frozen: -80°C or colder
Freeze-Dried: 2°C to 8°C
Live Culture: See Propagation Section
Type Strain 模式菌株 yes
Preceptrol? no
Genome Sequenced Strain Yes
Comments 注釋 Genome sequencing strain (Sanger Institute, UK).
Mitochondrial genome sequenced strain
Morphology After 3 days at 25°C colonies white to cream-colored, glistening, soft and smooth.  Cells are globose to ovoidal.
Medium 培養(yǎng)基 ATCC? Medium 28: Emmons' modification of Sabouraud's agar
ATCC? Medium 200: YM agar or YM broth
ATCC? Medium 1245: YEPD
Growth Conditions 生長條件
Temperature 培養(yǎng)溫度: 24°C to 26°C
Atmosphere 需氧情況: Typical aerobic
Sequenced Data
18S ribosomal RNA gene, partial sequence; internal   transcribed spacer 1, 5.8S ribosomal RNA gene, and internal transcribed spacer 2, complete sequence; and 26S ribosomal RNA gene, partial sequence
GGTGAACCTGCGGAAGGATCATTACTGATTTGCTTAATTGCACCACATGTGTTTTGTTCTGGACAAACTTGCTTTGGCGGTGGGCCCCTGCCTG
CCGCCAGAGGACATAAACTTACAACCAAATTTTTTATAAACTTGTCACGAGATTATTTTTAATAGTCAAAACTTTCAACAACGGATCTCTTGGTTC
TCGCATCGATGAAGAACGCAGCGAAATGCGATACGTAATATGAATTGCAGATATTCGTGAATCATCGAATCTTTGAACGCACATTGCGCCCTCTG
GTATTCCGGAGGGCATGCCTGTTTGAGCGTCGTTTCTCCCTCAAACCCCTAGGGTTTGGTGTTGAGCAATACGACTTGGGTTTGCTTGAAAGATG
ATAGTGGTATAAGGCGGAGATGCTTGACAATGGCTTAGGTGTAACCAAAAACATTGCTAAGGCGGTCTCTGGCGTCGCCCATTTTATTCTTCAAA
CTTTGACCTCAAATCAGGTAGGACTACCCGCTGAACTTAAGCATATCAATA


D1D2 region of the 26S ribosomal RNA gene
ATATCAATAAGCGGAGGAAAAGAAACCAACAGGGATTGCCTCAGTAGCGGCGAGTGAAGCGGCAAAAGCTCAAATTTGAAATCTGGCGTCTTT
GGCGTCCGAGTTGTAATTTGAAGAAGGTATCTTTGGGCCCGGCTCTTGTCTATGTTCCTTGGAACAGGACGTCACAGAGGGTGAGAATCCCGTG
CGATGAGATGGCCCGGGTCTATGTAAAGTTCCTTCGACGAGTCGAGTTGTTTGGGAATGCAGCTCTAAGTGGGTGGTAAATTCCATCTAAAGCT
AAATATTGGCGAGAGACCGATAGCGAACAAGTACAGTGATGGAAAGATGAAAAGAACTTTGAAAAGAGAGTGAAAAAGTACGTGAAATTGTTGA
AAGGGAAGGGCTTGAGATCAGACTTGGTATTTTGCAAGTTACTCTTTCGGGGGTGGCCTCTGCGGTTTACCGGGCCAGCATCGGTTTGGAGCGG
TAGGATAATGGCGGGGGAATGTGGCACGACTTTGGTTGTGTGTTATAGCCTCTGACGATACTGCCAGCCTAGACCGAGGACTGCGGTTTTTACC
TAGGATGTTGGCATAATGATCTTAAGTCGC

Morphology After 3 days at 25°C colonies white to cream-colored, glistening, soft and smooth.  Cells are globose to ovoidal.
Name of Depositor SA Meyer
Special Collection NCRR Contract
Chain of Custody ATCC <-- SA Meyer <-- CBS 7987 <-- D.C. Coleman CD 36
Isolation 分離基物 Oral cavity of HIV-infected patient, Dublin, Ireland
Cross References
Nucleotide (GenBank) : JQ070170 D1/D2 region of 28S rRNA gene
Nucleotide (GenBank) : JQ070103 ITS including 5.8S rRNA gene
References
Sullivan DJ, et al. Candida dubliniensis sp. nov.: phenotypic and molecular characterization of a novel species associated with oral candidosis in HIV-infected individuals. Microbiology 141: 1507-1521, 1995. PubMed: 7551019
Kurtzman CP, Robnett CJ. Identification of clinically important ascomycetous yeasts based on nucleotide divergence in the 5' end of the large-subunit (26S) ribosomal DNA gene. J Clin Microbiol 35: 1216-1223, 1997. PubMed: 9114410
Valach M, et al. Evolution of linear chromosomes and multipartite genomes in yeast mitochondria. Nucleic Acids Res. 39: 4202-4219, 2011. PubMed: 21266473
Cornet M, et al. Molecular identification of closely related Candida species using two ribosomal intergenic spacer fingerprinting methods. J Mol Diagn 13: 12-22, 2011. PubMed: 21227390
Arendrup MC, et al. Echinocandin susceptibility testing of Candida species: comparison of EUCAST EDef 7.1, CLSI M27-A3, Etest, disk diffusion, and agar dilution methods with RPMI and isosensitest media. Antimicrob. Agents Chemother 54: 426-439, 2010. PubMed: 19884370
Loaiza-Loeza S, et al. Differential expression of Candida dubliniensis-secreted aspartyl proteinase genes (CdSAP1-4) under different physiological conditions and during infection of a keratinocyte culture. FEMS Immunol Med Microbiol 56: 212-222, 2009. PubMed: 19538512
Jackson AP, et al. Comparative genomics of the fungal pathogens Candida dubliniensis and Candida albicans. Genome Res. 19: 2231-2244, 2009. PubMed: 19745113
Innings A, et al. Multiplex real-time PCR targeting the RNase P RNA gene for detection and identification of Candida species in blood. J Clin Microbiol 45: 874-880, 2007. PubMed: 17215340
Moran G, et al. Comparative genomics using Candida albicans DNA microarrays reveals absence and divergence of virulence-associated genes in Candida dubliniensis. Microbiology 150: 3363-3382, 2004. PubMed: 15470115
Diezmann S, et al. Phylogeny and evolution of medical species of Candida and related taxa: a multigenic analysis. J Clin Microbiol 42: 5624-5635, 2004. PubMed: 15583292
Pinjon E, et al. Molecular mechanisms of itraconazole resistance in Candida dubliniensis. Antimicrob. Agents Chemothe.r 47: 2424-2437, 2003. PubMed: 12878500
Perea S, et al. Molecular mechanisms of fluconazole resistance in Candida dubliniensis isolates from human immunodeficiency virus-infected patients with oropharyngeal candidiasis. Antimicrob Agents Chemother 46: 1695-1703, 2002. PubMed: 12019078
Tamura M, et al. Molecular characterization of new clinical isolates of Candida albicans and C. dubliniensis in Japan: analysis reveals a new genotype of C. albicans with group I intron. J. Clin. Microbiol. 39: 4309-4315, 2001. PubMed: 11724837
Yokoyama K, et al. Identification and phylogenetic relationship of the most common pathogenic Candida species inferred from mitochondrial cytochrome b gene sequences. J Clin Microbiol 38: 4503-4510, 2000. PubMed: 11101587
Heinz WJ, et al. Molecular responses to changes in the environmental pH are conserved between the fungal pathogens Candida dubliniensis and Candida albicans. Int J Med Microbiol 290: 231-238, 2000. PubMed: 10959725
Daniel HM, Sorrell TC, Meyer W. Partial sequence analysis of the actin gene and its potential for studying the phylogeny of Candida species and their teleomorphs. Int J Syst Evol Microbiol 51: 1593-1606, 2001. PubMed: 11491363
Staib P, et al. Isogenic strain construction and gene targeting in Candida dubliniensis. J. Bacteriol. 183: 2859-2865, 2001. PubMed: 11292806
Tintelnot K, et al. Evaluation of phenotypic markers for selection and identification of Candida dubliniensis. J. Clin. Microbiol. 38: 1599-1608, 2000. PubMed: 10747150
Tamura M, et al. New PCR primer pairs specific for Candida dubliniensis and detection of the fungi from the Candida albicans clinical isolates in Japan. Clin. Lab. 46: 33-40, 2000. PubMed: 10745979

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