ATCC? Number:50794?
Organism: Trypanosoma cruzi Chagas
Designations: M/HOM/BR/77/ESMERALDO CL3
Isolation: derived from strain Esmeraldo, originally isolated by xenodiagnosis from an acute case of Chagas' disease in a human male from northeastern Brazil, 1977, cloned by M. Miles
Depositors: JA Dvorak
History: ATCC<<--JA Dvorak<<--M.A. Miles
Biosafety Level:2
Shipped: frozen
Growth Conditions: ATCCmedium 1029: LIT mediumTemperature: 25.0°C Duration: axenic
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Comments: identification of isoenzyme patterns [47295] correlation of growth kinetics to zymodeme type [47296] flow cytometric analysis [47297] Brazilian and Bolivian zymodemes [47299] isoenzyme profile [47300]
Classification: KINGDOM: Protozoa
References: 47295: Miles MA, et al. The identification by isoenzyme patterns of two distinct strain-groups of Trypanosoma cruzi, circulating independently in a rural area of Brazil. Trans. R. Soc. Trop. Med. Hyg. 71: 217-225, 1977. PubMed: 407674 47296: Dvorak JA, et al. Trypanosoma cruzi: correlation of growth kinetics to zymodeme type in clones derived from various sources. J. Protozool. 27: 472-474, 1980. 47297: Dvorak JA, et al. Trypanosoma cruzi: flow cytometric analysis. I. Analysis of total DNA/organism by means of mithramycin-induced fluorescence. J. Protozool. 29: 430-437, 1982. PubMed: 6182288 47299: Tibayrenc M, Miles MA. A genetic comparison between Brazilian and Bolivian zymodemes of Trypanosoma cruzi. Trans. R. Soc. Trop. Med. Hyg. 77: 76-83, 1983. PubMed: 6344363 47300: Chapman MD, et al. Trypanosoma cruzi from the Paraguayan Chaco: isoenzyme profiles of strains isolated at Makthlawaiya. J. Protozool. 31: 482-486, 1984. PubMed: 6239030 48895: Miyahira Y, Dvorak JA. Kinetoplastidae display naturally occurring ancillary DNA-containing structures. Mol. Biochem. Parasitol. 65: 339-349, 1994. PubMed: 7969274 48897: Nozaki T, et al. Cellular and molecular biological analyses of nifurtimox resistance in Trypanosoma cruzi. Am. J. Trop. Med. Hyg. 55: 111-117, 1996. PubMed: 8702014 48898: McDaniel JP, Dvorak JA. Identification, isolation, and characterization of naturally-occurring Trypanosoma cruzi variants. Mol. Biochem. Parasitol. 57: 213-222, 1993. PubMed: 8433713 48901: Finley RW, Dvorak JA. Trypanosoma cruzi: analysis of the population dynamics of heterogeneous mixtures. J. Protozool. 34: 409-415, 1987. PubMed: 3323478 48904: Bongertz V, Dvorak JA. Trypanosoma cruzi: antigenic analysis of cloned stocks. Am. J. Trop. Med. Hyg. 32: 716-722, 1983. PubMed: 6349399 49375: Nozaki T, Dvorak JA. Intraspecific diversity in the response of Trypanosoma cruzi to environmental stress. J. Parasitol. 79: 451-454, 1993. PubMed: 8501607 49377: Nozaki T, Dvorak JA. Trypanosoma cruzi: flow cytometric analysis of developmental stage differences in DNA. J. Protozool. 38: 234-243, 1991. PubMed: 1880761