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ATCC? Number:50143?
Organism: Trichomonas vaginalis Donne
Designations: CDC 085
Isolation: human, Columbus, OH, 1980
Depositors: M Muller
History: ATCC<<--M Muller<<--J.G. Lossick
Biosafety Level:2
Shipped: frozen
Growth Conditions: ATCCmedium 2154: LYI Entamoeba mediumTemperature: 35.0℃ Duration: axenic; anaerobic Protocol: at pH 6.0
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Comments: metronidazole-resistant  [46485]  [58183] Antioxidant defences  [21764] phospholipid metabolism  [4649]
References:  4647: Lloyd D, Pedersen JZ. Metronidazole radical anion generation in vivo in Trichomonas vaginalis: oxygen quenching is enhanced in a drug-resistant strain.  J. Gen. Microbiol. 131: 87-92, 1985. PubMed: 2985740 4649: Beach DH, et al. Phospholipid metabolism of cultured Trichomonas vaginalis and Tritrichomonas foetus.  Mol. Biochem. Parasitol. 44: 97-108, 1991. PubMed: 2011157 21764: Ellis JE, et al. Antioxidant defences in the microaerophilic protozoan Trichomonas vaginalis: comparison of metronidazole-resistant and sensitive strains.  Microbiology 140: 2489-2494, 1994. PubMed: 7952198 23976: Muller M. Mode of action of metronidazole on anaerobic bacteria and protozoa.  Surgery 93: 165-171, 1983. PubMed: 6849201 32939: Vanacova S, et al. Characterization of Trichomonad species and strains by PCR fingerprinting.  J. Eukaryot. Microbiol. 44: 545-552, 1997. PubMed: 9435127 46485: Meri T, et al. Resistance of Trichomonas vaginalis to metronidazole: report of the first three cases from Finland and optimization of in vitro susceptibility testing under various oxygen concentrations.  J. Clin. Microbiol. 38: 763-767, 2000. PubMed: 10655382 58183: Muller M, et al. In vitro susceptibility of Trichomonas vaginalis to metronidazole and treatment outcome in vaginal trichomoniasis.  Sex. Transm. Dis. 15: 17-24, 1988. PubMed: 3258675 70353: Bouma MJ, et al. Activity of disulfiram (bis(diethylthiocarbamoyl)disulphide) and ditiocarb (diethyldithiocarbamate) against metronidazole-sensitive and -resistant Trichomonas vaginalis and Tritrichomonas foetus.  J. Antimicrob. Chemother. 42: 817-820, 1998. PubMed: 10052908 70372: Adagu IS, et al. In vitro activity of nitazoxanide and related compounds against isolates of Giardia intestinalis, Entamoeba histolytica and Trichomonas vaginalis.  J. Antimicrob. Chemother. 49: 103-111, 2002. PubMed: 11751773

metronidazole-resistant  [46485]  [58183] Antioxidant defences  [21764] phospholipid metabolism  [4649]