ATCC? Number:VR-2053?
Classification: Poxviridae, Orthopoxvirus
Agent: Vaccinia virus
Strain: vP-8 [recombinant Vaccinia virus]
Depositors: New York State Department of Health
Biosafety Level:2
Shipped: frozen
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Host Organism : HeLa cells (ATCCCCL-2); CV-1 (ATCCCCL-70); Vero (ATCCCCL-81); chicken embryo fibroblast
Effect : Yes, in vitro effects: Cytopathic effects in tissue culture
Comments : Recombinant vaccinia containing pBR322 insert at BamH1 site of HindIII F-fragment of VR-2031 (VTK-79). This is a recombinant vaccinia virus containing a pBR322 insert at the BamHI site of the HindIII F-fragment of VTK-79 (ATCCVR-2031). Plasmids can be introduced into this mutant by in vivo recombination. [13130]
References : 13123: Paoletti E, Panicali D. Modified vaccinia virus. US Patent 4,603,112 dated Jul 29 1986 13130: Paoletti E, Panicali D. Method for immunizing animals with synthetically modified vaccinia virus. US Patent 4,722,848 dated Feb 2 1988 13139: Panicali D, et al. Two major DNA variants present in serially propagated stocks of the WR strain of vaccinia virus. J. Virol. 37: 1000-1010, 1981. PubMed: 6262520