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首頁>美國ATCC>ATCC病毒類> vP-53 [strain VP53]
 vP-53 [strain VP53]
    vP-53 [strain VP53]
  • 平臺編號:bio-49425
  • 國際編號:ATCC VR-2060
  • 拉丁屬名: Vaccinia virus
  • 規(guī)格:frozen
  • 用途:ATCC原裝進口
  • 服務費用:
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  • 注意事項:僅用于科學研究或者工業(yè)應用等非醫(yī)療目的不可用于人類或動物的臨床診斷或治療,非藥用,非食用(產品信息以出庫為準)

ATCC? Number:VR-2060?
Classification: Poxviridae, Orthopoxvirus
Agent: Vaccinia virus
Strain: vP-53 [strain VP53]
Original Source: New York State Department of Health strain
Depositors: E Paoletti
Biosafety Level:2
Shipped: frozen
Permits/Forms: In addition to the MTA mentioned above, other ATCC and/or regulatory permits may be required for the transfer of this ATCC material. Anyone purchasing ATCC material is ultimately responsible for obtaining the permits. Please click here for information regarding the specific requirements for shipment to your location.
Host Organism : HeLa cells (ATCCCCL-2); CV-1 cells (ATCCCCL-70)
Effect : Yes, in vitro effects: Cytopathic effects in tissue culture
Comments : A recombinant of vaccinia (VTK-79), that contains an influenza HA gene. This clone expresses the HA gene more strongly than either vP-9 (ATCCVR-2043) or vP-10 (ATCCVR-2044). [13130] This clone expresses the hemagglutinin gene (serotype H1) of influenza virus and can be used in the production of antibodies against this protein. [13130] A HindIII fragment coding for the influenza HA gene (blunted, BamHI linkers added) was cloned into the BamHI site of a PstI subfragment of the vaccinia HindIII F-fragment. This construct was cloned into VTK-79 (ATCCVR-2031) by in vivo recombination. [13130]
References : 13123: Paoletti E, Panicali D. Modified vaccinia virus. US Patent 4,603,112 dated Jul 29 1986 13130: Paoletti E, Panicali D. Method for immunizing animals with synthetically modified vaccinia virus. US Patent 4,722,848 dated Feb 2 1988 13139: Panicali D, et al. Two major DNA variants present in serially propagated stocks of the WR strain of vaccinia virus. J. Virol. 37: 1000-1010, 1981. PubMed: 6262520

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