ATCC? Number:VR-724?
Classification: Retrovirus, Avian Type C Retrovirus Group
Agent: Rous sarcoma virus A
Strain: Schmidt-Ruppin (Subgroup A)
Original Source: chicken with fibrosarcoma
Depositors: W Okazaki, HG Purchase
Biosafety Level:2
Shipped: freeze-dried
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Host Organism : chicken embryo fibroblasts chicken embryo fibroblasts in tissue culture; chickens; most birds and mammals
Incubation : Temperature: 37.0°C Duration: 7 days
Effect : Yes, tumorigenicity: Transformation in chicken embryo fibroblasts in tissue culture Yes, tumorigenicity: sarcoma in chicken
Comments : Helper independent. This nondefective RSV likely containes significant amounts of src-deletion (transformation-defective) virus. Most workers would be better served by a molecular clone of SR-RSV-A such as ATCC45000, 45001, 45002 or 45003.
References : 33747: Morgan HR, Traub W. . Natl. Cancer Inst. Monogr. 17: 392, 1964. 33748: Vogt PK. Envelope classification of avian RNA tumor viruses. Bibl. Haematol. 36: 153-167, 1970. PubMed: 4376359 33850: Vogt PK. Avian tumor viruses. Adv. Virus Res. 11: 293-385, 1965. PubMed: 4285262