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ATCC? Number:VR-587?
Classification: Poxviridae, Chordopoxvirinae,Yatapoxvirus
Agent: Yaba monkey tumor virus deposited as Yaba monkey tumor virus, Yatapoxvirus
Strain: Roswell Park-Yohn
Original Source: Rhesus monkey, subcutaneous histiocytoma
Depositors: DS Yohn
Biosafety Level:2
Shipped: frozen
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Host Organism : CV-1 cells (ATCCCCL-70); rhesus monkey (in vivo) Primary cercopithecus monkey kidney cells in tissue culture; primary cynomolgus monkey kidney cells in tissue culture; rhesus monkey kidney cells in tissue culture
Incubation : Duration: 18 days at 35C (in vitro)
Effect : Yes, in vivo effects: causes tumor (Histiocytoma) in vivo, and microfoci at limiting dilution in CV-1 cells
Comments : Infected BS-C-1 cells (ATCCCCL-26) slowly develop cytoplasmic eosinophilic inclusions. Will not grow in Rhesus Kidney cells. Must by cultivated at 33-35C, will not grow at 37C. Has group antigen for Poxvirus, crosses slightly with vaccinia and monkeypox and is less stable. Does not hemagglutinate.
References : 33675: Yohn DS. . Nature 202: 881, 1964. 33677: Yohn DS, et al. Yaba tumor poxvirus synthesis in vitro. II. Adsorption, inactivation, and assay studies. J. Bacteriol. 91: 1953-1958, 1966. PubMed: 4287077 37337: Yohn DS, et al. Yaba tumor poxvirus synthesis in vitro. I. Cytopathological, histochemical, and immunofluorescent studies. J. Bacteriol. 91: 1977-1985, 1966. PubMed: 4287080 37338: Yohn DS, et al. Yaba tumor poxvirus synthesis in vitro. 3. Growth kinetics. J. Bacteriol. 91: 1986-1991, 1966. PubMed: 4287258