ATCC? Number:VR-1447?
Classification: Retrovirus, Mammalian Type C Retrovirus, Mammalian Group, Xenotropic
Agent: MuLv
Strain: pNFS Th-1
Original Source: Thymus of 5 and one-half month-old NFS swiss mouse
Depositors: JW Hartley
Biosafety Level:2
Shipped: frozen
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Host Organism : Mv 1 Lu (mink lung) cells (ATCCCCL-64) mink lung cells; many non-murine cells; M. dunni cells (ATCCCRL-2017)
Effect : Yes, in vitro effects: produces foci of round cells on Mink S+L- cells MiCl1(ATCCCCL-64.1), and plaque like foci on feline S+L- cell line :PG-4 ( ATCCCRL-2032)
Comments : This virus is maintained in persistently infected Mink lung cells which were originally transfected with molecularly cloned virus. Typical murine type C retrovirus. Although derived from endogenous sequences of inbred mice, it does not exogenously infect mouse cells, except certain cells of wild mouse origin such as M. dunni cells (ATCCCRL-2017). xenotropic
References : 33187: Buckler CE, et al. Cloning and characterization of an envelope-specific probe from xenotropic murine leukemia proviral DNA. J. Virol. 41: 228-236, 1982. PubMed: 6283115