ATCC? Number:VR-2310?
Agent: Mengovirus
Strain: pM16
Original Source: Genetically engineered Mengovirus having a shortened poly(C) tract
Depositors: Wisconsin Alumni Res. Fndn.
Biosafety Level:2
Shipped: blue ice
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Host Organism : H-HeLa cells monkeys; mouse; pigs, and H1Hela cells (ATCC-CRL-1958); BHK-21(C-13) cells (ATCCCCL-10); L-929 cells (ATCCCCL-1)
Effect : Yes, in vitro effects: Cytopathic effects in tissue culture
Comments : Recombinant cardiovirus attenuated by substitution of an artificially shortened poly(C) tract. Proposed as a vaccine against picornavirus diseases in non-murine mammals. The poly(C) tract of strain pM16 is 37 bases shorter than that of the wild-type Mengovirus. Note: Depositor recommends stocks NOT be stored frozen!
References : 33400: Palmenberg AC, et al. Method of inhibiting picornavirus disease. US Patent 5,229,111 dated Jul 20 1993