ATCC? Number:VR-59?
Classification: Picornaviridae, Enterovirus, Poliovirus
Agent: Human poliovirus 1 deposited as Poliovirus 1
Strain: LSa
Original Source: LS-a virus is a variant or mutant isolated from the Mahoney strain. (The Mahoney strain was isolated by T. Francis in 1941 from a pool of 3 stools from asymptomatic cases of poliomyelitis in Cleveland.)
Depositors: M Schaeffer
Biosafety Level:3
Shipped: freeze-dried
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Host Organism : mouse, i. s. inoculation; LLC-MK2 cells (ATCCCCL-7) mouse; monkey, i. s. inoculation; monkey kidney cells
Incubation : Duration: 2-10 days
Effect : Yes, in vitro effects: Cytopathic effects in tissue culture Yes, in vivo effects: paralysis in mouse
Comments : [The BMBL notes that all laboratory personnel working directly with the agent must have documented polio vaccination or demonstrated serologic evidence of immunity to all three poliovirus types. (CDC/NIH Biosafety in Microbiological and Biomedical Laboratories, 4th ed, 1999 - stock no. 017-040-00547-4)].
Related Products: antiserum:ATCC VR-1001AS/HO