ATCC? Number:VR-2128?
Classification: Nidovirales, Coronaviridae, Coronavirus, Group 1
Agent: Feline coronavirus deposited as Feline infectious peritonitis virus
Strain: FIPV-1146, P50
Original Source: FIPV-WSU-1146 isolated from a neonatal kitten, Washington State University (McKeirnan & Evermann, 1979)
Depositors: FW Scott
Biosafety Level:2
Shipped: frozen
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Host Organism : A-72 canine cells (ATCCCRL-1542) A-72 cells (ATCCCRL-1542); feline cell lines such as fcwf-4; CRFK cells (ATCCCCL-94)
Incubation : Duration: 1-2 days at 34C
Effect : Yes, in vitro effects: Cytopathic effects in tissue culture (A-72 cultures)
Comments : Zoopathogenic. This holding (VR-2128), VR-2167 and VR-2126 are attenuated derivatives of VR-2125, FIPV 79-1146. Patent deposit. Cross reacts with canine coronavirus, TGE virus of swine and Human coronavirus 229E. For background information see Pederson et al. (1984: Adv. Exp. Med. Biol., 173: 365-380) and U.S. Patent No. 4,195,130. Zoopathogenic. This holding (VR-2128), VR-2167 and VR-2126 are attenuated derivatives of VR-2125, FIPV 79-1146.
References : 24673: Pedersen NC, et al. Pathogenicity studies of feline coronavirus isolates 79-1146 and 79-1683. Am. J. Vet. Res. 45: 2580-2585, 1984. PubMed: 6084432 33377: McKeirnan AJ, et al. Isolation of Feline Coronaviruses from Two Cats with Diverse Disease Manifestations. Feline Pract. 11: 16-20, 1981. 33378: Baldwin CA, Scott FW. Feline infectious peritonitis vaccine and method of preparation. US Patent 5,043,157 dated Aug 27 1991