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ATCC? Number:VR-716?
Classification: Adenoviridae, Mastadenovirus, Human adenovirus B
Agent: Human adenovirus 34 deposited as Adenovirus type 34
Strain: Compton
Original Source: Human urine, 1972
Depositors: JC Hierholzer
Biosafety Level:2
Shipped: frozen
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Host Organism : HEp-2 cells (ATCCCCL-23) WI-38 cells (ATCCCCL-75); human embryonic lung fibroblast; RU-1 cells (human embryonic lung); primary human amnion cells; primary human embryonic kidney cells; KB cells (ATCCCCL-17); HEp-2 cells (ATCCCCL-23)
Incubation : Temperature: 35.0°C Duration: 3 days
Effect : Yes, in vitro effects: Cytopathic effects (typical adenovirus CPE)
Comments : The virus has been placed in Rosen's HA group 1, subgroup 1a. No HAI or SN cross with types 1 through 33; high HAI cross between AV-34 virus and AV-35 sera; moderate HAI cross between AV-35 cirus and AV-34 sera. The adenovirion, with typical morphology and CF and HA activities, has a buoyant density of 1.340 g/ml; average diameter, excluding projections is 73 nm. Partially heat labile at pH 7.0 with or without 1 M MgCl[2]. The virus has been placed in Rosen's HA group 1, subgroup 1a. No HAI or SN cross with types 1 through 33; high HAI cross between AV-34 virus and AV-35 sera; moderate HAI cross between AV-35 cirus and AV-34 sera.
References : 24654: Hierholzer JC, et al. New human adenovirus isolated from a renal transplant recipient: description and characterization of candiate adenovirus type 34. J. Clin. Microbiol. 1: 366-376, 1975. PubMed: 170313 24704: Hierholzer JC, et al. Antigenic relationships among the 47 human adenoviruses determined in reference horse antisera. Arch. Virol. 121: 179-197, 1991. PubMed: 1759904 32356: Ma Y, Mathews MB. Structure, function, and evolution of adenovirus-associated RNA: a phylogenetic approach. J. Virol. 70: 5083-5099, 1996. PubMed: 8764016