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ATCC? Number:VR-2160?
Classification: Herpesvirus, Bovine
Agent: Infectious bovine rhinotracheitis
Strain: beta gal INV tk(-) IBRV
Original Source: Parental virus was ATCCVR-188, LA strain, from dairy cattle in California. An intermediate in the formation of beta-gal INV was VR-2006
Depositors: S Kit
Biosafety Level:2
Shipped: frozen
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Host Organism : RAB-9 cells (ATCCCRL-1414) rabbit skin and in tissue culture, bovine tracheal cells and bovine kidney cells
Effect : Yes, in vitro effects: Cytopathic effects in tissue culture
Store at : -70C
Comments : This strain is an IBR-vaccine candidate. It is temperature-sensitive AND due to a 3 kb insertion of E. coli K12 beta-galactosidase in the tk gene is tk(-). This strain is an IBR-vaccine candidate. It is temperature-sensitive AND due to a 3 kb insertion of E. coli K12 beta-galactosidase in the tk gene is tk(-).
References : 33212: Madin SH, et al. Isolation of the infectious bovine rhinotracheitis virus. Science 124: 721-722, 1956. PubMed: 13371311 33379: Kit M, Kit S. Infectious bovine rhinotracheitis virus insertion mutants, vaccines containing same, and methods for the production of same. US Patent 5,601,816 dated Feb 11 1997