ATCC? Number:VR-2269?
Classification: Baculovirus
Agent: Nuclear polyhedrosis virus, Autographa californica
Strain: AcCC2
Original Source: Nuclear polyhedrosis virus, Autographa californica recombinant with human alpha-galactosidase A precursor gene
Depositors: DH Calhoun
Biosafety Level:2
Shipped: frozen
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Host Organism : Sf9 cells (ATCCCRL-1711) many Lepidopterm insect cell lines
Effect : Yes, in vitro effects: Expanded nuclei in enlarged cells (25 - 50% increase in diameter). Lysis at late times p.i
Store at : -70C
Comments : AcCC1 and AcCC2 are plague purified occlusion negative recombinant baculovirus resulting from the co-transfection of Sf-9 cells with pCC4 (transfer vector) and AcMNPV DNA.
References : 21036: Calhoun DH, Coppola G. Recombinant alpha-galactosidase A therapy for Fabry disease. US Patent 5,179,023 dated Jan 12 1993