Candida tropicalis (Castellani) Berkhout菌株拉丁名
(ATCC® 750™) 菌株編號
Strain Designations 菌株別名 : [1909, ATCC 4563, ATCC 7349, CBS 94, CCRC 20520, IFO 1070, IFO 1400, JCM 1541, NRRL Y-12699, NRRL Y-12968, NRRL Y-607] /
Product Format 提供形式 : freeze-dried
Deposited As Monilia tropicalis (Castellani) Castellani et Chalmers
Application 用途 Assay of chloro-8-quinolinol
Bacterial resistance testing
Degrades xylose D-xylose
Fungus resistance testing adhesives
Produces aspartic proteinases aspartyl proteinases
Produces ethyl alcohol ethanol
Produces xylitol Susceptibility disc testing Susceptibility testing
Produces xylitol from D-xylose
Control strain for typing systems
Produces ethanol from D-xylose
Control strain to test oxygen availability in bioreactor in space laboratory
Reference 參考文獻(xiàn) strain for Clinical and Laboratory Standards Institute(CLSI)-developed Antifungal Susceptibility Testing.
Biosafety Level 生物安全等級 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. Product Format freeze-dried
Storage Conditions 生長條件
Frozen（冷凍物）: -80℃ or colder
Freeze-Dried（凍干物）: 2℃ to 8℃
Live Culture: See Propagation Section
Type Strain 模式菌株 yes
Preceptrol® yes
Genome Sequenced Strain Yes
Ploidy diploid
Comments 注釋 Fluconazole-sensitive Utilizes phenol, catechol and 3- and 4-methylcatechols as sole carbon source Esterase activity MIC of 2-hydroxychalcone, 75 mcg/ml Adherence to lysophospholipids Genome sequencing strain (Genolevures Consortium, France; Wellcome Trust Sanger Institute, UK). For additional infromation, see CLSI M27-A2 (Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts; Approved Standards-Second Edition). Mitochondrial genome sequenced strain
Medium 培養(yǎng)基 ATCC® Medium 200: YM agar or YM broth
ATCC® Medium 28: Emmons' modification of Sabouraud's agar
Growth Conditions 生長條件
Temperature 培養(yǎng)溫度 : 24℃ to 26℃
Atmosphere 需氧情況 : Typical aerobic
Sequenced Data 18S ribosomal RNA gene, partial sequence; internal transcribed spacer 1, 5.8S ribosomal RNA gene, and internal transcribed spacer 2, complete sequence; and 26S ribosomal RNA gene, partial sequence GGAAGGATCATTACTGATTTGCTTA
ATTGCACCACATGTGTTTTTTATTGAACAAAT
TTCTTTGGTGGCGGGAGCAATCCTACCGCCAGAGGTTAT
AACTAAACCAAACTTTTTA
TTTACAGTCAAACTTGATTTATTATTACAATAG
TCAAAACTTTCAACAACGGATCTCTTGGTTCTCGCAT
CGATGAAGAACGCAGCGAAATGCGATACGT
AATATGAATTGCAGATATTCGTGAATCATCGAATCTTTGAACGCA
CATTGCGCCCTTTGGTATTCCAAAGGGCATGCCTGTTTGAGCGTCAT
TTCTCCCTCAAACCCCCGGGTTTGGTGTTGAGCAATACGCTAGGTTTGTT
TGAAAGAATTTAACGTGGAAACTTATTTTAA
GCGACTTAGGTTTATCCAAAAACGCTTATTTTGCTAGTGGC
CACCACAATTTATTTCATAACTTTGACCTCAAATCAGGTAGGACTACC
CGCTGAACTTAAGCATATCAATAA D1D2 region of the 26S ribosomal RNA gene ATATCAATAAGCGGAGGAAAAGAAACCAACAGGG
ATTGCCTTAGTAGCGGCGAGTGAAGCGGCAAAAGCTCAAATTTGAAATC
TGGCTCTTTCAGAGTCCGAGTTGTAATTTGAAGAAGGTATCTTTGGGTC
TGGCTCTTGTCTATGTTTCTTGGAACAGAACGTCACAGA
GGGTGAGAATCCCGTGCGATGAGATGATCCAGGCCTATGTAAA
GTTCCTTCGAAGAGTCGAGTTGTTTGGGAATGCAGCTCTAAGTGGGTGGT
AAATTCCATCTAAAGCTAAATATTGGCGAGAGACCGATAGCGAACAAGTACAGTG
ATGGAAAGATGAAAAGAACTTTGAAAAGAGAGTGAAAAAGTA
CGTGAAATTGTTGAAAGGGAAGGGCTTGAGATCAGACTTGGTATTTTGTATG
TTACTTCTTCGGGGGTGGCCTCTACAGTTTATCGGG
CCAGCATCAGTTTGGGCGG
TAGGAGAATTGCGTTGGAATGTGGCACGGCTTCGGTTGTGTGT
TATAGCCTTCGTCGATACTGCCAGCCTAGACTGAGGACTGCGGTTTATACCTAG
GATGTTGGCATAATGATCTTAAGTCGC
Name of Depositor 收藏者 A Castellani
Isolation 分離源 Patient with bronchomycosis
Cross References
Nucleotide (GenBank) : KU729064 ITS including 5.8S rRNA gene
Nucleotide (GenBank) : KU729147 D1/D2 region of 26S rRNA gene
Nucleotide (GenBank) : AX110837 Sequence 1570 from Patent WO0123604.
Nucleotide (GenBank) : U45749 26S ribosomal RNA gene, partial sequence
Nucleotide (GenBank) : M60308 C. tropicalis small subunit ribosomal RNA.
Nucleotide (GenBank) : M23673 Candida tropicalis (ATCC 750) cytochrome P450 lanosterol
Nucleotide (GenBank) : AF194419 Candida tropicalis multidrug resistance protein (MDR1) gene,
Nucleotide (GenBank) : AF218992 Candida tropicalis strain ATCC 750T 5.8S ribosomal RNA gene,
Nucleotide (GenBank) : M15945 Yeast (C. tropicalis) P450alk gene encoding the alkane-inducible
Nucleotide (GenBank) : M35199 C. tropicalis NADPH-cytochrome P450 reductase gene, complete cds. Nucleotide (GenBank) : M24894 Candida tropicalis alkane-inducible cytochrome P450 gene, complete Nucleotide (GenBank) : U00675 Candida tropicalis D-arabinitol dehydrogenase (ARD) gene, complete References Mahmourides, G et al. Ethanol accumulation in cultures of Pachysolen tannophilus on D-xylose is associated with a transition to a state of low oxygen consumption. Bio-Technology 3: 59-62, 1985. Walther I, et al. Development of a miniature bioreactor for continuous culture in a space laboratory. J Biotechnol 38: 21-32, 1994. PubMed: 7765579
Sato M, et al. Growth inhibitory properties of chalcones to Candida. Lett Appl Microbiol 18: 53-55, 1994. Rudek W. Esterase activity in Candida species. J Clin Microbiol 8: 756-759, 1978. PubMed: 370150
Castellani A. Observations on "tropical broncho-oidiosis". Br Med J 2: 868-869, 1910. Lentz DL, et al. The anticandidal properties of chlorinated 8-quinolinols. Mycologia 88: 651-654, 1996.
J Gen Appl Microbiol 19: 171-187, 1973. Prakobphol A, et al. Specific adherence of Candida tropicalis to lysophospholipids. Biochemistry 33: 9496-9503, 1994. PubMed: 8068624
Vazquez JA, et al. Comparison of restriction enzyme analysis versus pulsed-field gradient gel electrophoresis as a typing system for Torulopsis glabrata and Candida species other than C. albicans. J Clin Microbiol 31: 2021-2030, 1993. PubMed: 8396585
Brenner DJ, et al. Multisite reproducibility of colorimetric broth microdilution method for antifungal susceptibility testing of yeast isolates. J Clin Microbiol 32: 1625-1628, 1994. PubMed: 7929747
Pfaller MA, et al. Selection of candidate quality control isolates and tentative quality control ranges for in vitro susceptibility testing of yeast isolates by National Committee for Clinical Laboratory Standards proposed standard methods. J Clin Microbiol 32: 1650-1653, 1994. PubMed: 7929752
ASTM International Standard Test Methods for Resistance of Adhesive Preparations in Container to Attack by Bacteria, Yeast, and Fungi. West Conshohocken, PA:ASTM International;ASTM Standard Test Method D 4783-01e1. Winkelhausen E, Kuzmanova S. Microbial conversion of D-xylose to xylitol. J Ferment Bioeng 86: 1-14, 1998.
de Viragh PA, et al. Cloning and sequencing of two Candida parapsilosis genes encoding acid proteases. J Gen Microbiol 139: 335-342, 1993. PubMed: 8436951 Sanglard D, Fiechter A. DNA transformations of Candida tropicalis with replicating and integrative vectors. Yeast 8: 1065-1075, 1992. PubMed: 1293885
Barchiese F, et al. Experimental induction of fluconazole resistance in Candida tropicalis ATCC 750. Antimicrob Agents Chemother 44: 1578-1584, 2000. PubMed: 10817712
Kurtzman CP, Robnett CJ. Identification of clinically important ascomycetous yeasts based on nucleotide divergence in the 5' end of the large-subunit (26S) ribosomal DNA gene. J Clin Microbiol 35: 1216-1223, 1997. PubMed: 9114410
Zaugg C, et al. Secreted aspartic proteinase family of Candida tropicalis. Infect Immun 69: 405-412, 2001. PubMed: 11119531
Method for Antifungal Disk Diffusion Susceptibility Testing of Yeast; Approved Guideline. Wayne, PA. Clinical and Laboratory Standards Institute; CLSI M44-A2.
Medical microbiology--Susceptibility testing of microbial pathogens to antimicrobial agents -- Part 84: Microdilution; Special requirements for testing of fungi against antifungal agents. Berlin, Germany:Deutsches Institut fur Normung;DIN DIN 58940-84: 2002, 2002
Souciet JL, et al. Genomic Exploration of the Hemiascomycetous Yeasts: 1. A set of yeast species for molecular evolution studies. FEBS Lett. 487: 3-12, 2000.
Blandin G, et al. Genomic Exploration of the Hemiascomycetous Yeasts: 16. Candida tropicalis. FEBS Lett 487: 91-94, 2000. Valach M, et al. Evolution of linear chromosomes and multipartite genomes in yeast mitochondria. Nucleic Acids Res. 39: 4202-4219, 2011.
Forastiero A, et al. Candida tropicalis antifungal cross-resistance is related to different azole target (Erg11p) modifications. Antimicrob Agents Chemother 57: 4769-4781, 2013. PubMed: 23877676
Bisha B, Kim HJ, Brehm-Stecher BF. Improved DNA-FISH for cytometric detection of Candida spp. J Appl Microbiol 110: 881-892, 2011. PubMed: 21205104 Cornet M, et al. Molecular identification of closely related Candida species using two ribosomal intergenic spacer fingerprinting methods. J Mol Diagn 13: 12-22, 2011. PubMed: 21227390
Kurtzman CP, Suzuki M. Phylogenetic analysis of ascomycete yeasts that form coenzyme Q-9 and the proposal of the new genera Babjeviella, Meyerozyma, Millerozyma, Priceomyces, and Scheffersomyces. Mycoscience 51: 2-14, 2010.
Gunisova S, et al. Identification and comparative analysis of telomerase RNAs from Candida species reveal conservation of functional elements. RNA 15: 546-559, 2009. PubMed: 19223441
Desnos-Ollivier M, et al. Clonal population of flucytosine-resistant Candida tropicalis from blood cultures, Paris, France. Emerg Infect Dis 14: 557-565, 2008. PubMed: 18394272
Innings A, et al. Multiplex real-time PCR targeting the RNase P RNA gene for detection and identification of Candida species in blood. J Clin Microbiol 45: 874-880, 2007. PubMed: 17215340
Leinberger DM, et al. Development of a DNA microarray for detection and identification of fungal pathogens involved in invasive mycoses. J Clin Microbiol 43: 4943-4953, 2005. PubMed: 16207946
Diezmann S, et al. Phylogeny and evolution of medical species of Candida and related taxa: a multigenic analysis. J Clin Microbiol 42: 5624-5635, 2004. PubMed: 15583292
