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Streptomyces avermitilis (ex Burg et al.) Kim and Goodfellow 拉丁名

(ATCC? 31267?) 統(tǒng)一編號

Deposited As Streptomyces avermitilis

Strain Designations 菌種別名 NRRL 8165 [JCM 5070, MA-4680, NCIMB 12804]

Application 用途 Produces avermectin avermectins, avermectin B(1)a C-076, and C-076 and derivatives. Isolation Soil, Ito City, Shizuoka Pref., Japan Biosafety Level 1 Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Product Format  提供形式 freeze-dried

Storage Conditions 保藏條件

Frozen 冷凍物: -80℃ or colder

Freeze-Dried 凍干物: 2℃ to 8℃

Live Culture 活物: See Propagation Section

Disclosure This material is cited in a US or other Patent and may not be used to infringe the claims. Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished. This material may not have been produced or characterized by ATCC. Preceptrol? no Genome Sequenced Strain Streptomyces avermitilis MA-4680 DNA, complete genome.

Type Strain 模式菌株 yes

Comments 注釋 Genome sequenced strain

Medium 培養(yǎng)基 ATCC? Medium 184: Glucose asparagine agar

Growth Conditions 生長條件

Temperature 培養(yǎng)溫度: 26℃

Atmosphere 需氧情況: Aerobic

Name of Depositor 寄存人 NRRL U.S. Patent Number 4,378,353

Disclosure This material is cited in a US or other Patent and may not be used to infringe the claims. Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished. This material may not have been produced or characterized by ATCC. Special Collection NSF - Bacteriology

Chain of Custody 來源國家 ATCC <-- NRRL <-- Merck & Co., Inc. MA-4680 Isolation Soil, Ito City, Shizuoka Pref., Japan

References 參考文獻 Burg RW, et al. Avermectins, new family of potent anthelmintic agents: Producing organism and fermentation. Antimicrob. Agents Chemother. 15: 361-367, 1979. PubMed: 464561 Goegelman RT, et al. Novel C-076 compounds. US Patent 4,378,353 dated Mar 26 1983 Ikeda H, et al. Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis. Nat. Biotechnol. 21: 526-531, 2003. PubMed: 12692562 Kim SB, Goodfellow M. Streptomyces avermitilis sp. nov., nom. rev., a taxonomic home for the avermectin-producing streptomycetes. Int. J. Syst. Evol. Microbiol. 52: 2011-2014, 2002. PubMed: 12508861

Miller TW, et al. Avermectins, new family of potent anthelmintic agents: Isolation and chromatographic properties. Antimicrob. Agents Chemother. 15: 368-371, 1979. PubMed: 464562

Ormond RE. 22-Hydroxy derivatives of C-076 compounds, pharmaceutical compositions and method of use. US Patent 4,412,991 dated Nov 1 1983

Cross References Nucleotide (GenBank) : AY029771 Streptomyces avermitilis ribosomal protein S12 (rpsL) gene, complete cds.

Nucleotide (GenBank) : BA000030 Streptomyces avermitilis MA-4680 DNA, complete genome.