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Pimelobacter simplex (Jensen) Suzuki and Komagata 拉丁名

(ATCC® 6946™) 統(tǒng)一編號

Deposited As Corynebacterium simplex Jensen 

Strain Designations 菌種別名 NCTC 4215 [BUCSAV 385, CDA 835, FHP 534, NCIB 8929] 

Application 用途 Degrades levulinic acid Produces 3-keto-delta-1,4 steroids 

Produces 5'-nucleotides Produces 7-cyano steroids 

Produces oxoalkylxanthines oxoalkylxanthine 

Produces pregnadienes Produces 5'-nucleotides by growth on hydrocarbons and subsequent degradation of intracellular RNA at alkaline pH Reduction of 3-methoxy-8(14)-seco-1,3,5(10),9(11)-estratetraene-14, 17-dione 

Reduction of 4-chloro-1-(4-fluorophenyl)butan-1-one Dehydrogenation of Reichstein's compound S and hydrocortisone 

Isolation 分離源 Rice soil 

Biosafety Level 生物安全等級 1 

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. 

Product Format 提供形式 freeze-dried 

Preceptrol® no 

Type Strain 模式菌株 yes Ref, Ref, Ref 

Medium 培養(yǎng)基 ATCC® Medium 3: Nutrient agar or nutrient broth 

Growth Conditions 生長條件 

Temperature 培養(yǎng)溫度 : 26.0°C

Name of Depositor 寄存人 NCTC 

Chain of Custody 來源國家 ATCC <<--NCTC<<--H.L. Jensen 

Isolation 分離源 Rice soil 

References 參考文獻(xiàn) Nesemann G, et al. Microbiological process for the preparation of oxoalkylxanthines. Canadian Patent 1,022,867 

Nobile A. Process for production of dienes by corynebacteria. US Patent 2,837,464 dated Jun 3 1958 

Nakao Y, Kuno M. Method for the production of 5'-nucleotides. US Patent 3,652,395 dated Mar 28 1972 

Badia DJ, Sardinas JL. Oxidation of steroid compounds in presence of antibiotics. US Patent 3,010,876 

dated Nov 28 1961 Bowers A, Ringold HJ. 7-Cyano steroids. US Patent 3,050,534 dated Aug 21 1962 

Ueno T, Harada M. Method for removing levulinic acid by microorganisms. US Patent 3,663,368 

dated May 16 1972 Nesemann G, et al. Mikrobiologisches Verfahren zur Herstellung von Oxoalkylxanthinen. 

German Federal Republic Patent 2,302,772 Casas-Campillo C. 

Process for the transformation of steroids using a mutant strain of Arthrobacter (Corynebacterium) simplex. 

US Patent 3,264,194 dated Aug 2 1966 Gibian H, et al. Production of optically active antipodes. 

US Patent 3,562,112 dated Feb 9 1971 Validation list no. 12. Int. J. Syst. Bacteriol. 33: 896-897, 1983. 

Proc. Linn. Soc. N.S.W. 58: 181, 1933. 

Montes MC, Magana I. Delta'-dehydrogenation of steroids by Arthrobacter simplex immobilized in calcium polygalacturonate beads. J. Ind. Microbiol. 8: 259-264, 1991. PubMed: 1367800 

O'Donnell AG, et al. Lipids in the classification of Nocardioides: reclassification of Arthrobacter simplex (Jensen) lochhead in the genus Nocardioides (Prauser) emend. 

O'Donnell et al. as Nocardioides simplex comb. nov.. Arch. Microbiol. 133: 323-329, 1982. PubMed: 7171289 

Patel RN, et al. Microbial reduction of 1-(4-fluorophenyl)-4-[4-(5-fluoro-2-pyrimidinyl)-1-piperazinyl]butan-1-one. Biotechnol. Appl. Biochem. 17: 139-153, 1993. PubMed: 8166884 

Skerman VB, et al. Approved lists of bacterial names. Int J Syst Bacteriol 30: 225-420, 1980. 

Cremers FP, et al. An autosomal homologue of the choroideremia gene colocalizes with the usher syndorme type II locus on the distal part of chromosome 1q. Hum. Mol. Genet. 1: 71-75, 1992. PubMed: 1301160 

Validation list no. 12. Int. J. Syst. Bacteriol. 33: 896-897, 1983. 

O'Donnell AG, et al. Lipids in the classification of Nocardioides: reclassification of Arthrobacter simplex (Jensen) lochhead in the genus 

Nocardioides (Prauser) emend. O'Donnell et al. as Nocardioides simplex comb. nov.. Arch. Microbiol. 133: 323-329, 1982. PubMed: 7171289 

Skerman VB, et al. Approved lists of bacterial names. Int J Syst Bacteriol 30: 225-420, 1980. 

Cross References Nucleotide (GenBank) : M16174 P.simplex 5S rRNA. Nucleotide (GenBank) : M37693 Arthobacter simplex small subunit ribosomal RNA.