細(xì)胞名稱:人乳腺癌細(xì)胞他莫西酚耐藥株LCC2
產(chǎn)品規(guī)格:T25培養(yǎng)瓶x1或1.5ml凍存管x2
細(xì)胞數(shù)量:1x10^6或1x10^6
保存溫度;37℃或-198℃
運(yùn)輸方式:常溫保溫運(yùn)輸或干冰運(yùn)輸
安全等級:1
用途限制:僅供科研3類
培養(yǎng)體系:90%DMEM+10%FBS+1%三抗
培養(yǎng)溫度:37℃
二氧化碳濃度:5%
簡介
人乳腺癌細(xì)胞他莫西酚耐藥株LCC2取自69歲女性供體,耐藥倍數(shù)17。
注釋:倍增時間34h:
基因突變:/
HLA信息:/
STR信息:/
參考文獻(xiàn):PubMed=8324732
Brunner N.,Frandsen T.L.,Holst-Hansen C.,Bei M.,Thompson E.W.,Wakeling A.E.,Lippman M.E.,Clarke R.
MCF7/LCC2:a 4-hydroxytamoxifen resistant human breast cancer variant that retains sensitivity to the steroidal antiestrogen ICI 182,780.
Cancer Res.53:3229-3232(1993)
PubMed=11078910;DOI=10.1016/S0304-3835(00)00579-6
Lilling G.,Hacohen H.,Nordenberg J.,Livnat T.,Rotter V.,Sidi Y.
Differential sensitivity of MCF-7 and LCC2 cells,to multiple growth inhibitory agents:possible relation to high bcl-2/bax ratio?
Cancer Lett.161:27-34(2000)
PubMed=23868472;DOI=10.1038/ncomms3175
Johansson H.J.,Sanchez B.C.,Mundt F.,Forshed J.,Kovacs A.,Panizza E.,Hultin-Rosenberg L.,Lundgren B.,Martens U.,Mathe G.,Yakhini Z.,Helou K.,Krawiec K.,Kanter L.,Hjerpe A.,Stal O.,Linderholm B.K.,Lehtio J.
Retinoic acid receptor alpha is associated with tamoxifen resistance in breast cancer.
Nat.Commun.4:2175-2175(2013)