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平臺(tái)編號(hào)：bio-123152
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細(xì)胞信息： SU-DHL-5
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規(guī)格：1×10?cells/T25培養(yǎng)瓶
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用途：細(xì)胞系
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服務(wù)費(fèi)用：
加載中…… - 訂購(gòu)
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注意事項(xiàng)：僅用于科學(xué)研究或者工業(yè)應(yīng)用等非醫(yī)療目的不可用于人類或動(dòng)物的臨床診斷或治療，非藥用，非食用（產(chǎn)品信息以出庫(kù)為準(zhǔn)）
人彌漫性大B細(xì)胞淋巴瘤細(xì)胞
細(xì)胞名稱：人彌漫性大B細(xì)胞淋巴瘤細(xì)胞SU-DHL-5
產(chǎn)品規(guī)格：T25培養(yǎng)瓶x1；1.5ml凍存管x2
細(xì)胞數(shù)量：1x10^6：1x10^6
保存溫度：37℃；-198℃
運(yùn)輸方式：常溫保溫運(yùn)輸；干冰運(yùn)輸
安全等級(jí)：1
用途限制
僅供科研2類培養(yǎng)體系
培養(yǎng)體系DMEM高糖培養(yǎng)基+10%FBS+1%三抗
培養(yǎng)溫度37℃
二氧化碳濃度5%
簡(jiǎn)介
人彌漫性大B細(xì)胞淋巴瘤細(xì)胞SU-DHL-5取自17歲女性供體，該細(xì)胞源于DSMZ
注釋
Part of:Cancer Cell Line Encyclopedia(CCLE)project.
Part of:COSMIC cell lines project.
Part of:MD Anderson Cell Lines Project.
Characteristics:Genetic heterogeneous,consists of 2 subclones(PubMed=27566572).
Doubling time:~40 hours(DSMZ).
Microsatellite instability:Stable(MSS)(Sanger).
Omics:Array-based CGH.
Omics:CNV analysis.
Omics:Deep exome analysis.
Omics:Deep RNAseq analysis.
Omics:DNA methylation analysis.
Omics:miRNA expression profiling.
Omics:Protein expression by reverse-phase protein arrays.
Omics:SNP array analysis.
Omics:Transcriptome analysis.
Omics:Virome analysis using RNAseq.
Derived from sampling site:Lymph node.
基因突變
HLA信息
/
STR信息
Amelogenin X
CSF1PO 11,13
D3S1358 15,16
D5S818 12,15
D7S820 10
D8S1179 13,15
D13S317 12
D16S539 11,13
D18S51 13,15
D21S11 28,30
FGA 22,23
Penta D 11,12
Penta E 5,19
TH01 6,9
TPOX 8
vWA 17
參考文獻(xiàn)
PubMed=27566572;DOI=10.18632/oncotarget.11524
Quentmeier H.,Pommerenke C.,Ammerpohl O.,Geffers R.,Hauer V.,MacLeod R.A.F.,Nagel S.,Romani J.,Rosati E.,Rosen A.,Uphoff C.C.,Zaborski M.,Drexler H.G.
Subclones in B-lymphoma cell lines:isogenic models for the study of gene regulation.
Oncotarget 7:63456-63465(2016)
PubMed=28196595;DOI=10.1016/j.ccell.2017.01.005
Li J.,Zhao W.,Akbani R.,Liu W.,Ju Z.,Ling S.,Vellano C.P.,Roebuck P.,Yu Q.,Eterovic A.K.,Byers L.A.,Davies M.A.,Deng W.,Gopal Y.N.V.,Chen G.,von Euw E.M.,Slamon D.J.,Conklin D.,Heymach J.V.,Gazdar A.F.,Minna J.D.,Myers J.N.,Lu Y.,Mills G.B.,Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)
PubMed=30285677;DOI=10.1186/s12885-018-4840-5
Tan K.-T.,Ding L.-W.,Sun Q.-Y.,Lao Z.-T.,Chien W.,Ren X.,Xiao J.-F.,Loh X.-Y.,Xu L.,Lill M.,Mayakonda A.,Lin D.-C.,Yang H.,Koeffler H.P.
Profiling the B/T cell receptor repertoire of lymphocyte derived cell lines.
BMC Cancer 18:940-940(2018)
PubMed=30894373;DOI=10.1158/0008-5472.CAN-18-2747
Dutil J.,Chen Z.,Monteiro A.N.,Teer J.K.,Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res.79:1263-1273(2019)
PubMed=31068700;DOI=10.1038/s41586-019-1186-3
Ghandi M.,Huang F.W.,Jane-Valbuena J.,Kryukov G.V.,Lo C.C.,McDonald E.R.III,Barretina J.,Gelfand E.T.,Bielski C.M.,Li H.,Hu K.,Andreev-Drakhlin A.Y.,Kim J.,Hess J.M.,Haas B.J.,Aguet F.,Weir B.A.,Rothberg M.V.,Paolella B.R.,Lawrence M.S.,Akbani R.,Lu Y.,Tiv H.L.,Gokhale P.C.,de Weck A.,Mansour A.A.,Oh C.,Shih J.,Hadi K.,Rosen Y.,Bistline J.,Venkatesan K.,Reddy A.,Sonkin D.,Liu M.,Lehar J.,Korn J.M.,Porter D.A.,Jones M.D.,Golji J.,Caponigro G.,Taylor J.E.,Dunning C.M.,Creech A.L.,Warren A.C.,McFarland J.M.,Zamanighomi M.,Kauffmann A.,Stransky N.,Imielinski M.,Maruvka Y.E.,Cherniack A.D.,Tsherniak A.,Vazquez F.,Jaffe J.D.,Lane A.A.,Weinstock D.M.,Johannessen C.M.,Morrissey M.P.,Stegmeier F.,Schlegel R.,Hahn W.C.,Getz G.,Mills G.B.,Boehm J.S.,Golub T.R.,Garraway L.A.,Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)
產(chǎn)品規(guī)格：T25培養(yǎng)瓶x1；1.5ml凍存管x2
細(xì)胞數(shù)量：1x10^6：1x10^6
保存溫度：37℃；-198℃
運(yùn)輸方式：常溫保溫運(yùn)輸；干冰運(yùn)輸
安全等級(jí)：1
用途限制
僅供科研2類培養(yǎng)體系
培養(yǎng)體系DMEM高糖培養(yǎng)基+10%FBS+1%三抗
培養(yǎng)溫度37℃
二氧化碳濃度5%
簡(jiǎn)介
人彌漫性大B細(xì)胞淋巴瘤細(xì)胞SU-DHL-5取自17歲女性供體，該細(xì)胞源于DSMZ
注釋
Part of:Cancer Cell Line Encyclopedia(CCLE)project.
Part of:COSMIC cell lines project.
Part of:MD Anderson Cell Lines Project.
Characteristics:Genetic heterogeneous,consists of 2 subclones(PubMed=27566572).
Doubling time:~40 hours(DSMZ).
Microsatellite instability:Stable(MSS)(Sanger).
Omics:Array-based CGH.
Omics:CNV analysis.
Omics:Deep exome analysis.
Omics:Deep RNAseq analysis.
Omics:DNA methylation analysis.
Omics:miRNA expression profiling.
Omics:Protein expression by reverse-phase protein arrays.
Omics:SNP array analysis.
Omics:Transcriptome analysis.
Omics:Virome analysis using RNAseq.
Derived from sampling site:Lymph node.
基因突變
HLA信息
/
STR信息
Amelogenin X
CSF1PO 11,13
D3S1358 15,16
D5S818 12,15
D7S820 10
D8S1179 13,15
D13S317 12
D16S539 11,13
D18S51 13,15
D21S11 28,30
FGA 22,23
Penta D 11,12
Penta E 5,19
TH01 6,9
TPOX 8
vWA 17
參考文獻(xiàn)
PubMed=27566572;DOI=10.18632/oncotarget.11524
Quentmeier H.,Pommerenke C.,Ammerpohl O.,Geffers R.,Hauer V.,MacLeod R.A.F.,Nagel S.,Romani J.,Rosati E.,Rosen A.,Uphoff C.C.,Zaborski M.,Drexler H.G.
Subclones in B-lymphoma cell lines:isogenic models for the study of gene regulation.
Oncotarget 7:63456-63465(2016)
PubMed=28196595;DOI=10.1016/j.ccell.2017.01.005
Li J.,Zhao W.,Akbani R.,Liu W.,Ju Z.,Ling S.,Vellano C.P.,Roebuck P.,Yu Q.,Eterovic A.K.,Byers L.A.,Davies M.A.,Deng W.,Gopal Y.N.V.,Chen G.,von Euw E.M.,Slamon D.J.,Conklin D.,Heymach J.V.,Gazdar A.F.,Minna J.D.,Myers J.N.,Lu Y.,Mills G.B.,Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)
PubMed=30285677;DOI=10.1186/s12885-018-4840-5
Tan K.-T.,Ding L.-W.,Sun Q.-Y.,Lao Z.-T.,Chien W.,Ren X.,Xiao J.-F.,Loh X.-Y.,Xu L.,Lill M.,Mayakonda A.,Lin D.-C.,Yang H.,Koeffler H.P.
Profiling the B/T cell receptor repertoire of lymphocyte derived cell lines.
BMC Cancer 18:940-940(2018)
PubMed=30894373;DOI=10.1158/0008-5472.CAN-18-2747
Dutil J.,Chen Z.,Monteiro A.N.,Teer J.K.,Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res.79:1263-1273(2019)
PubMed=31068700;DOI=10.1038/s41586-019-1186-3
Ghandi M.,Huang F.W.,Jane-Valbuena J.,Kryukov G.V.,Lo C.C.,McDonald E.R.III,Barretina J.,Gelfand E.T.,Bielski C.M.,Li H.,Hu K.,Andreev-Drakhlin A.Y.,Kim J.,Hess J.M.,Haas B.J.,Aguet F.,Weir B.A.,Rothberg M.V.,Paolella B.R.,Lawrence M.S.,Akbani R.,Lu Y.,Tiv H.L.,Gokhale P.C.,de Weck A.,Mansour A.A.,Oh C.,Shih J.,Hadi K.,Rosen Y.,Bistline J.,Venkatesan K.,Reddy A.,Sonkin D.,Liu M.,Lehar J.,Korn J.M.,Porter D.A.,Jones M.D.,Golji J.,Caponigro G.,Taylor J.E.,Dunning C.M.,Creech A.L.,Warren A.C.,McFarland J.M.,Zamanighomi M.,Kauffmann A.,Stransky N.,Imielinski M.,Maruvka Y.E.,Cherniack A.D.,Tsherniak A.,Vazquez F.,Jaffe J.D.,Lane A.A.,Weinstock D.M.,Johannessen C.M.,Morrissey M.P.,Stegmeier F.,Schlegel R.,Hahn W.C.,Getz G.,Mills G.B.,Boehm J.S.,Golub T.R.,Garraway L.A.,Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)
