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平臺編號：bio-129776
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細(xì)胞信息： SK-UT-1
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規(guī)格：1×10?cells/T25培養(yǎng)瓶
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用途：/
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服務(wù)費用：
加載中…… - 訂購
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注意事項：僅用于科學(xué)研究或者工業(yè)應(yīng)用等非醫(yī)療目的不可用于人類或動物的臨床診斷或治療，非藥用，非食用（產(chǎn)品信息以出庫為準(zhǔn)）
人子宮平滑肌肉瘤細(xì)胞SK-UT-1
細(xì)胞名稱：人子宮平滑肌肉瘤細(xì)胞SK-UT-1
產(chǎn)品規(guī)格：T25培養(yǎng)瓶x1；1.5ml凍存管x2
細(xì)胞數(shù)量：1x10^6；1x10^6
保存溫度：37℃；-198℃
運輸方式：常溫保溫運輸；干冰運輸
安全等級：1
用途限制：僅供科研3類
培養(yǎng)體系：DMEM高糖（HYCLONE SH30022.01）+10%FBS+1%三抗
培養(yǎng)溫度：37℃
二氧化碳濃度：5%
簡介：人子宮平滑肌肉瘤細(xì)胞SK-UT-1取自75歲女性供體。該細(xì)胞保藏于ATCC
注釋
Part of:Cancer Cell Line Encyclopedia(CCLE)project.
Part of:COSMIC cell lines project.
From:Memorial Sloan Kettering Cancer Center;New York;USA.
Registration:Memorial Sloan Kettering Cancer Center Office of Technology Development;SK1980-537.
Microsatellite instability:Instable(MSI-high)(PubMed=31068700;Sanger).
Omics:Deep exome analysis.
Omics:Deep RNAseq analysis.
Omics:DNA methylation analysis.
Omics:SNP array analysis.
Omics:Transcriptome analysis.
基因突變
Heterozygous for APC p.Gln1096Ter(c.3286C>T)and p.Thr1556fs*9(c.4666delA)(ATCC).
Heterozygous for PIK3CA p.Arg88Gln(c.263G>A)(ATCC).
Heterozygous for PTEN p.Thr319fs*1(c.955_958delACTT)(V317fs*3)and p.Asn323fs*2(c.968_969insA)(ATCC).
Homozygous for RB1 p.Val654fs*4(c.1959delA)(ATCC).
Heterozygous for TP53 p.Arg175His(c.524G>A)(ClinVar=VCV000012374)and p.Arg248Gln(c.743G>A)(ClinVar=VCV000012356)(PubMed=2216456;ATCC).
HLA信息
/
STR信息
Amelogenin X
CSF1PO 10,11
D3S1358 15,16
D5S818 10,11
D7S820 9,10
D8S1179 13,15
D13S317 13
D16S539 13,14
D18S51 11,16
D21S11 29,32.2
FGA 22,24
Penta D 11,15
Penta E 17
TH01 7
TPOX 8
vWA 15,16
參考文獻
PubMed=27397505;DOI=10.1016/j.cell.2016.06.017
Iorio F.,Knijnenburg T.A.,Vis D.J.,Bignell G.R.,Menden M.P.,Schubert M.,Aben N.,Goncalves E.,Barthorpe S.,Lightfoot H.,Cokelaer T.,Greninger P.,van Dyk E.,Chang H.,de Silva H.,Heyn H.,Deng X.,Egan R.K.,Liu Q.,Mironenko T.,Mitropoulos X.,Richardson L.,Wang J.,Zhang T.,Moran S.,Sayols S.,Soleimani M.,Tamborero D.,Lopez-Bigas N.,Ross-Macdonald P.,Esteller M.,Gray N.S.,Haber D.A.,Stratton M.R.,Benes C.H.,Wessels L.F.A.,Saez-Rodriguez J.,McDermott U.,Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)
PubMed=30894373;DOI=10.1158/0008-5472.CAN-18-2747
Dutil J.,Chen Z.,Monteiro A.N.,Teer J.K.,Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res.79:1263-1273(2019)
PubMed=31068700;DOI=10.1038/s41586-019-1186-3
Ghandi M.,Huang F.W.,Jane-Valbuena J.,Kryukov G.V.,Lo C.C.,McDonald E.R.III,Barretina J.,Gelfand E.T.,Bielski C.M.,Li H.,Hu K.,Andreev-Drakhlin A.Y.,Kim J.,Hess J.M.,Haas B.J.,Aguet F.,Weir B.A.,Rothberg M.V.,Paolella B.R.,Lawrence M.S.,Akbani R.,Lu Y.,Tiv H.L.,Gokhale P.C.,de Weck A.,Mansour A.A.,Oh C.,Shih J.,Hadi K.,Rosen Y.,Bistline J.,Venkatesan K.,Reddy A.,Sonkin D.,Liu M.,Lehar J.,Korn J.M.,Porter D.A.,Jones M.D.,Golji J.,Caponigro G.,Taylor J.E.,Dunning C.M.,Creech A.L.,Warren A.C.,McFarland J.M.,Zamanighomi M.,Kauffmann A.,Stransky N.,Imielinski M.,Maruvka Y.E.,Cherniack A.D.,Tsherniak A.,Vazquez F.,Jaffe J.D.,Lane A.A.,Weinstock D.M.,Johannessen C.M.,Morrissey M.P.,Stegmeier F.,Schlegel R.,Hahn W.C.,Getz G.,Mills G.B.,Boehm J.S.,Golub T.R.,Garraway L.A.,Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)
細(xì)胞操作說明下載：細(xì)胞操作說明
產(chǎn)品規(guī)格：T25培養(yǎng)瓶x1；1.5ml凍存管x2
細(xì)胞數(shù)量：1x10^6；1x10^6
保存溫度：37℃；-198℃
運輸方式：常溫保溫運輸；干冰運輸
安全等級：1
用途限制：僅供科研3類
培養(yǎng)體系：DMEM高糖（HYCLONE SH30022.01）+10%FBS+1%三抗
培養(yǎng)溫度：37℃
二氧化碳濃度：5%
簡介：人子宮平滑肌肉瘤細(xì)胞SK-UT-1取自75歲女性供體。該細(xì)胞保藏于ATCC
注釋
Part of:Cancer Cell Line Encyclopedia(CCLE)project.
Part of:COSMIC cell lines project.
From:Memorial Sloan Kettering Cancer Center;New York;USA.
Registration:Memorial Sloan Kettering Cancer Center Office of Technology Development;SK1980-537.
Microsatellite instability:Instable(MSI-high)(PubMed=31068700;Sanger).
Omics:Deep exome analysis.
Omics:Deep RNAseq analysis.
Omics:DNA methylation analysis.
Omics:SNP array analysis.
Omics:Transcriptome analysis.
基因突變
Heterozygous for APC p.Gln1096Ter(c.3286C>T)and p.Thr1556fs*9(c.4666delA)(ATCC).
Heterozygous for PIK3CA p.Arg88Gln(c.263G>A)(ATCC).
Heterozygous for PTEN p.Thr319fs*1(c.955_958delACTT)(V317fs*3)and p.Asn323fs*2(c.968_969insA)(ATCC).
Homozygous for RB1 p.Val654fs*4(c.1959delA)(ATCC).
Heterozygous for TP53 p.Arg175His(c.524G>A)(ClinVar=VCV000012374)and p.Arg248Gln(c.743G>A)(ClinVar=VCV000012356)(PubMed=2216456;ATCC).
HLA信息
/
STR信息
Amelogenin X
CSF1PO 10,11
D3S1358 15,16
D5S818 10,11
D7S820 9,10
D8S1179 13,15
D13S317 13
D16S539 13,14
D18S51 11,16
D21S11 29,32.2
FGA 22,24
Penta D 11,15
Penta E 17
TH01 7
TPOX 8
vWA 15,16
參考文獻
PubMed=27397505;DOI=10.1016/j.cell.2016.06.017
Iorio F.,Knijnenburg T.A.,Vis D.J.,Bignell G.R.,Menden M.P.,Schubert M.,Aben N.,Goncalves E.,Barthorpe S.,Lightfoot H.,Cokelaer T.,Greninger P.,van Dyk E.,Chang H.,de Silva H.,Heyn H.,Deng X.,Egan R.K.,Liu Q.,Mironenko T.,Mitropoulos X.,Richardson L.,Wang J.,Zhang T.,Moran S.,Sayols S.,Soleimani M.,Tamborero D.,Lopez-Bigas N.,Ross-Macdonald P.,Esteller M.,Gray N.S.,Haber D.A.,Stratton M.R.,Benes C.H.,Wessels L.F.A.,Saez-Rodriguez J.,McDermott U.,Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)
PubMed=30894373;DOI=10.1158/0008-5472.CAN-18-2747
Dutil J.,Chen Z.,Monteiro A.N.,Teer J.K.,Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res.79:1263-1273(2019)
PubMed=31068700;DOI=10.1038/s41586-019-1186-3
Ghandi M.,Huang F.W.,Jane-Valbuena J.,Kryukov G.V.,Lo C.C.,McDonald E.R.III,Barretina J.,Gelfand E.T.,Bielski C.M.,Li H.,Hu K.,Andreev-Drakhlin A.Y.,Kim J.,Hess J.M.,Haas B.J.,Aguet F.,Weir B.A.,Rothberg M.V.,Paolella B.R.,Lawrence M.S.,Akbani R.,Lu Y.,Tiv H.L.,Gokhale P.C.,de Weck A.,Mansour A.A.,Oh C.,Shih J.,Hadi K.,Rosen Y.,Bistline J.,Venkatesan K.,Reddy A.,Sonkin D.,Liu M.,Lehar J.,Korn J.M.,Porter D.A.,Jones M.D.,Golji J.,Caponigro G.,Taylor J.E.,Dunning C.M.,Creech A.L.,Warren A.C.,McFarland J.M.,Zamanighomi M.,Kauffmann A.,Stransky N.,Imielinski M.,Maruvka Y.E.,Cherniack A.D.,Tsherniak A.,Vazquez F.,Jaffe J.D.,Lane A.A.,Weinstock D.M.,Johannessen C.M.,Morrissey M.P.,Stegmeier F.,Schlegel R.,Hahn W.C.,Getz G.,Mills G.B.,Boehm J.S.,Golub T.R.,Garraway L.A.,Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)
細(xì)胞操作說明下載：細(xì)胞操作說明
