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平臺編號：bio-131660
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細胞信息： YD-10B
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規(guī)格：1×10?cells/T25培養(yǎng)瓶
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服務費用：
加載中…… - 訂購
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注意事項：僅用于科學研究或者工業(yè)應用等非醫(yī)療目的不可用于人類或動物的臨床診斷或治療，非藥用，非食用（產品信息以出庫為準）
人口腔舌鱗癌細胞YD-10B
細胞名稱：人口腔舌鱗癌細胞YD-10B
產品規(guī)格：T25培養(yǎng)瓶x1；1.5ml凍存管x2
細胞數量：1x10^6；1x10^6
保存溫度：37℃；-198℃
運輸方式：常溫保溫運輸；干冰運輸
安全等級：1
用途限制：僅供科研2類
培養(yǎng)體系：DMEM高糖培養(yǎng)基+10%FBS+1%三抗
培養(yǎng)溫度：37℃
二氧化碳濃度：5%
簡介：人口腔舌鱗癌細胞YD-10B取自67歲男性供體。
注釋
Part of:Cancer Cell Line Encyclopedia(CCLE)project.
Doubling time:25.3 hours(PubMed=16264262).
Omics:Deep exome analysis.
Omics:Deep RNAseq analysis.
Omics:SNP array analysis.
Omics:Transcriptome analysis.
基因突變
Heterozygous for CDKN2A p.Glu88Ter(c.262G>T)and p.Trp110Ter(c.330G>A)(p.Gly125Arg;c.373G>A)(CCLE).
Homozygous for TP53 p.Tyr236Ter(c.708C>A)(PubMed=16264262;CCLE).
HLA信息：/
STR信息
Amelogenin X,Y
CSF1PO 12,13
D3S1358 17
D5S818 11,13
D7S820 11
D8S1179 11
D13S317 8,9(KCLB)
9(PubMed=16264262)
D16S539 10,11
D18S51 14
D21S11 30,32
DXS101 22
FGA 23
Penta D 8,9
Penta E 5,8
TH01 6,9
TPOX 8
vWA 18,19,20(PubMed=16264262)
18,19(KCLB)
參考文獻
PubMed=16264262;DOI=10.1038/emm.2005.48
Lee E.J.,Kim J.,Lee S.A.,Kim E.-J.,Chun Y.-C.,Ryu M.H.,Yook J.-I.
Characterization of newly established oral cancer cell lines derived from six squamous cell carcinoma and two mucoepidermoid carcinoma cells.
Exp.Mol.Med.37:379-390(2005)
PubMed=17404023;DOI=10.1196/annals.1397.014
Kwak Y.E.,Jeon N.K.,Kim J.,Lee E.J.
The cyclooxygenase-2 selective inhibitor celecoxib suppresses proliferation and invasiveness in the human oral squamous carcinoma.
Ann.N.Y.Acad.Sci.1095:99-112(2007)
PubMed=22460905;DOI=10.1038/nature11003
Barretina J.G.,Caponigro G.,Stransky N.,Venkatesan K.,Margolin A.A.,Kim S.,Wilson C.J.,Lehar J.,Kryukov G.V.,Sonkin D.,Reddy A.,Liu M.,Murray L.,Berger M.F.,Monahan J.E.,Morais P.,Meltzer J.,Korejwa A.,Jane-Valbuena J.,Mapa F.A.,Thibault J.,Bric-Furlong E.,Raman P.,Shipway A.,Engels I.H.,Cheng J.,Yu G.K.,Yu J.,Aspesi P.Jr.,de Silva M.,Jagtap K.,Jones M.D.,Wang L.,Hatton C.,Palescandolo E.,Gupta S.,Mahan S.,Sougnez C.,Onofrio R.C.,Liefeld T.,MacConaill L.E.,Winckler W.,Reich M.,Li N.,Mesirov J.P.,Gabriel S.B.,Getz G.,Ardlie K.,Chan V.,Myer V.E.,Weber B.L.,Porter J.,Warmuth M.,Finan P.,Harris J.L.,Meyerson M.,Golub T.R.,Morrissey M.P.,Sellers W.R.,Schlegel R.,Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)
PubMed=23708675;DOI=10.3892/ijo.2013.1953
Oh J.-E.,Kim J.-O.,Shin J.-Y.,Zhang X.-H.,Won H.-S.,Chun S.-H.,Jung C.-K.,Park W.-S.,Nam S.-W.,Eun J.-W.,Kang J.-H.
Molecular genetic characterization of p53 mutated oropharyngeal squamous cell carcinoma cells transformed with human papillomavirus E6 and E7 oncogenes.
Int.J.Oncol.43:383-393(2013)
PubMed=30894373;DOI=10.1158/0008-5472.CAN-18-2747
Dutil J.,Chen Z.,Monteiro A.N.,Teer J.K.,Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res.79:1263-1273(2019)
PubMed=31068700;DOI=10.1038/s41586-019-1186-3
Ghandi M.,Huang F.W.,Jane-Valbuena J.,Kryukov G.V.,Lo C.C.,McDonald E.R.III,Barretina J.,Gelfand E.T.,Bielski C.M.,Li H.,Hu K.,Andreev-Drakhlin A.Y.,Kim J.,Hess J.M.,Haas B.J.,Aguet F.,Weir B.A.,Rothberg M.V.,Paolella B.R.,Lawrence M.S.,Akbani R.,Lu Y.,Tiv H.L.,Gokhale P.C.,de Weck A.,Mansour A.A.,Oh C.,Shih J.,Hadi K.,Rosen Y.,Bistline J.,Venkatesan K.,Reddy A.,Sonkin D.,Liu M.,Lehar J.,Korn J.M.,Porter D.A.,Jones M.D.,Golji J.,Caponigro G.,Taylor J.E.,Dunning C.M.,Creech A.L.,Warren A.C.,McFarland J.M.,Zamanighomi M.,Kauffmann A.,Stransky N.,Imielinski M.,Maruvka Y.E.,Cherniack A.D.,Tsherniak A.,Vazquez F.,Jaffe J.D.,Lane A.A.,Weinstock D.M.,Johannessen C.M.,Morrissey M.P.,Stegmeier F.,Schlegel R.,Hahn W.C.,Getz G.,Mills G.B.,Boehm J.S.,Golub T.R.,Garraway L.A.,Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)
產品規(guī)格：T25培養(yǎng)瓶x1；1.5ml凍存管x2
細胞數量：1x10^6；1x10^6
保存溫度：37℃；-198℃
運輸方式：常溫保溫運輸；干冰運輸
安全等級：1
用途限制：僅供科研2類
培養(yǎng)體系：DMEM高糖培養(yǎng)基+10%FBS+1%三抗
培養(yǎng)溫度：37℃
二氧化碳濃度：5%
簡介：人口腔舌鱗癌細胞YD-10B取自67歲男性供體。
注釋
Part of:Cancer Cell Line Encyclopedia(CCLE)project.
Doubling time:25.3 hours(PubMed=16264262).
Omics:Deep exome analysis.
Omics:Deep RNAseq analysis.
Omics:SNP array analysis.
Omics:Transcriptome analysis.
基因突變
Heterozygous for CDKN2A p.Glu88Ter(c.262G>T)and p.Trp110Ter(c.330G>A)(p.Gly125Arg;c.373G>A)(CCLE).
Homozygous for TP53 p.Tyr236Ter(c.708C>A)(PubMed=16264262;CCLE).
HLA信息：/
STR信息
Amelogenin X,Y
CSF1PO 12,13
D3S1358 17
D5S818 11,13
D7S820 11
D8S1179 11
D13S317 8,9(KCLB)
9(PubMed=16264262)
D16S539 10,11
D18S51 14
D21S11 30,32
DXS101 22
FGA 23
Penta D 8,9
Penta E 5,8
TH01 6,9
TPOX 8
vWA 18,19,20(PubMed=16264262)
18,19(KCLB)
參考文獻
PubMed=16264262;DOI=10.1038/emm.2005.48
Lee E.J.,Kim J.,Lee S.A.,Kim E.-J.,Chun Y.-C.,Ryu M.H.,Yook J.-I.
Characterization of newly established oral cancer cell lines derived from six squamous cell carcinoma and two mucoepidermoid carcinoma cells.
Exp.Mol.Med.37:379-390(2005)
PubMed=17404023;DOI=10.1196/annals.1397.014
Kwak Y.E.,Jeon N.K.,Kim J.,Lee E.J.
The cyclooxygenase-2 selective inhibitor celecoxib suppresses proliferation and invasiveness in the human oral squamous carcinoma.
Ann.N.Y.Acad.Sci.1095:99-112(2007)
PubMed=22460905;DOI=10.1038/nature11003
Barretina J.G.,Caponigro G.,Stransky N.,Venkatesan K.,Margolin A.A.,Kim S.,Wilson C.J.,Lehar J.,Kryukov G.V.,Sonkin D.,Reddy A.,Liu M.,Murray L.,Berger M.F.,Monahan J.E.,Morais P.,Meltzer J.,Korejwa A.,Jane-Valbuena J.,Mapa F.A.,Thibault J.,Bric-Furlong E.,Raman P.,Shipway A.,Engels I.H.,Cheng J.,Yu G.K.,Yu J.,Aspesi P.Jr.,de Silva M.,Jagtap K.,Jones M.D.,Wang L.,Hatton C.,Palescandolo E.,Gupta S.,Mahan S.,Sougnez C.,Onofrio R.C.,Liefeld T.,MacConaill L.E.,Winckler W.,Reich M.,Li N.,Mesirov J.P.,Gabriel S.B.,Getz G.,Ardlie K.,Chan V.,Myer V.E.,Weber B.L.,Porter J.,Warmuth M.,Finan P.,Harris J.L.,Meyerson M.,Golub T.R.,Morrissey M.P.,Sellers W.R.,Schlegel R.,Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)
PubMed=23708675;DOI=10.3892/ijo.2013.1953
Oh J.-E.,Kim J.-O.,Shin J.-Y.,Zhang X.-H.,Won H.-S.,Chun S.-H.,Jung C.-K.,Park W.-S.,Nam S.-W.,Eun J.-W.,Kang J.-H.
Molecular genetic characterization of p53 mutated oropharyngeal squamous cell carcinoma cells transformed with human papillomavirus E6 and E7 oncogenes.
Int.J.Oncol.43:383-393(2013)
PubMed=30894373;DOI=10.1158/0008-5472.CAN-18-2747
Dutil J.,Chen Z.,Monteiro A.N.,Teer J.K.,Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res.79:1263-1273(2019)
PubMed=31068700;DOI=10.1038/s41586-019-1186-3
Ghandi M.,Huang F.W.,Jane-Valbuena J.,Kryukov G.V.,Lo C.C.,McDonald E.R.III,Barretina J.,Gelfand E.T.,Bielski C.M.,Li H.,Hu K.,Andreev-Drakhlin A.Y.,Kim J.,Hess J.M.,Haas B.J.,Aguet F.,Weir B.A.,Rothberg M.V.,Paolella B.R.,Lawrence M.S.,Akbani R.,Lu Y.,Tiv H.L.,Gokhale P.C.,de Weck A.,Mansour A.A.,Oh C.,Shih J.,Hadi K.,Rosen Y.,Bistline J.,Venkatesan K.,Reddy A.,Sonkin D.,Liu M.,Lehar J.,Korn J.M.,Porter D.A.,Jones M.D.,Golji J.,Caponigro G.,Taylor J.E.,Dunning C.M.,Creech A.L.,Warren A.C.,McFarland J.M.,Zamanighomi M.,Kauffmann A.,Stransky N.,Imielinski M.,Maruvka Y.E.,Cherniack A.D.,Tsherniak A.,Vazquez F.,Jaffe J.D.,Lane A.A.,Weinstock D.M.,Johannessen C.M.,Morrissey M.P.,Stegmeier F.,Schlegel R.,Hahn W.C.,Getz G.,Mills G.B.,Boehm J.S.,Golub T.R.,Garraway L.A.,Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)
