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平臺編號：bio-68433
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國際編號：HB-8568?
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細胞信息： Mab 126
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規(guī)格：frozen
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用途：ATCC原裝細胞
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服務(wù)費用：
加載中…… - 訂購
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注意事項：僅用于科學(xué)研究或者工業(yè)應(yīng)用等非醫(yī)療目的不可用于人類或動物的臨床診斷或治療，非藥用，非食用（產(chǎn)品信息以出庫為準）
Mab 126
ATCC Number：HB-8568?
是否是腫瘤細胞：0
物種來源：小鼠
細胞形態(tài)：淋巴樣
免疫類型：IgM
運輸方式：凍存運輸
數(shù)量：大量
生長狀態(tài)：懸浮生長
規(guī)格：0.1ml Designations: Mab 126
Depositors: ?Scripps Clinic and Research Foundation
Isotype: IgM
Biosafety Level:1
Shipped: frozen
Medium & Serum: See Propagation Growth Properties:suspension
Organism: Mus musculus (B cell); Mus musculus (myeloma) deposited as mouse (B cell); mouse (myeloma)
Morphology:lymphoblast
Source: Cell Type: hybridoma: B lymphocyte;
Cellular Products:immunoglobulin; monoclonal antibody; against ganglioside GD2
Permits/Forms:In addition to the MTA mentioned above, other ATCC and/or regulatory permits may be required for the transfer of this ATCC material. Anyone purchasing ATCC material is ultimately responsible for obtaining the permits. Please click here for information regarding the specific requirements for shipment to your location.
Tumorigenic:Yes
Comments:Animals were immunized with neuroblastoma cells (LAN-1).
Spleen cells were fused with P3X63Ag8 myeloma cells.
Ganglioside GD2 is strongly expressed on cells of tumors of neuroectodermal origin (especially neuroblastoma and melanoma cells).
The antibody reacts strongly with neuroblastoma and melanoma cells, but does not react with lymphomas, sarcomas and most carcinomas.
Faint reactivity was reported for small cell carcinomas, adenocarcinomas of the adrenal cortex, gliomas and normal neural and muscle tissue.
Propagation: ATCC complete growth medium: The base medium for this cell line is ATCC-formulated Dulbecco's Modified Eagle's Medium, Catalog No. 30-2002. To make the complete growth medium, add the following components to the base medium: fetal bovine serum to a final concentration of 10%.
Subculturing: Medium Renewal: Every 2 to 3 days
Cultures can be maintained by addition or replacement of fresh medium. Start cultures at 2 X 10 exp5 cells/ml and maintain between 1 X 10 exp5 and 1 X 10 exp6 cells/ml.
References: 3599: Reisfeld RA. Monoclonal antibody directed to human ganglioside GD2. US Patent 4,675,287 dated Jun 23 1987
是否是腫瘤細胞：0
物種來源：小鼠
細胞形態(tài)：淋巴樣
免疫類型：IgM
運輸方式：凍存運輸
數(shù)量：大量
生長狀態(tài)：懸浮生長
規(guī)格：0.1ml Designations: Mab 126
Depositors: ?Scripps Clinic and Research Foundation
Isotype: IgM
Biosafety Level:1
Shipped: frozen
Medium & Serum: See Propagation Growth Properties:suspension
Organism: Mus musculus (B cell); Mus musculus (myeloma) deposited as mouse (B cell); mouse (myeloma)
Morphology:lymphoblast
Source: Cell Type: hybridoma: B lymphocyte;
Cellular Products:immunoglobulin; monoclonal antibody; against ganglioside GD2
Permits/Forms:In addition to the MTA mentioned above, other ATCC and/or regulatory permits may be required for the transfer of this ATCC material. Anyone purchasing ATCC material is ultimately responsible for obtaining the permits. Please click here for information regarding the specific requirements for shipment to your location.
Tumorigenic:Yes
Comments:Animals were immunized with neuroblastoma cells (LAN-1).
Spleen cells were fused with P3X63Ag8 myeloma cells.
Ganglioside GD2 is strongly expressed on cells of tumors of neuroectodermal origin (especially neuroblastoma and melanoma cells).
The antibody reacts strongly with neuroblastoma and melanoma cells, but does not react with lymphomas, sarcomas and most carcinomas.
Faint reactivity was reported for small cell carcinomas, adenocarcinomas of the adrenal cortex, gliomas and normal neural and muscle tissue.
Propagation: ATCC complete growth medium: The base medium for this cell line is ATCC-formulated Dulbecco's Modified Eagle's Medium, Catalog No. 30-2002. To make the complete growth medium, add the following components to the base medium: fetal bovine serum to a final concentration of 10%.
Subculturing: Medium Renewal: Every 2 to 3 days
Cultures can be maintained by addition or replacement of fresh medium. Start cultures at 2 X 10 exp5 cells/ml and maintain between 1 X 10 exp5 and 1 X 10 exp6 cells/ml.
References: 3599: Reisfeld RA. Monoclonal antibody directed to human ganglioside GD2. US Patent 4,675,287 dated Jun 23 1987
